Day

September 25, 2025

Biomarker Testing – Metabolic Panel

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Metabolic Health Panel

Version 1.0 | As at: 25 Sep 2025

Biomarkers

Panels

This panel evaluates glucose control, lipid balance, and metabolic resilience. It helps identify early warning signs of energy dysregulation, overtraining, or long‑term health risks.

  • Supports safe fueling and recovery strategies
  • Flags insulin resistance, dyslipidemia, or metabolic stress
  • Guides nutrition timing and macronutrient balance
  • Provides context for fatigue, weight changes, and adaptation

🚨 Red‑Flag Results — Seek Medical Review: Fasting glucose >6.1 mmol/L • HbA1c >6.5% • Triglycerides >2.0 mmol/L • ALT/AST >2× upper limit

⏱ When to Test

  • Morning, fasted (8–12 h, water only)
  • At least 48 h after heavy training or racing
  • Well hydrated, no acute illness
  • Recommended scenarios: start-of-base, pre/post camp, quarterly check, unexplained fatigue or weight change

🧬 Athlete Targets

Marker Standard Range Athlete Target Notes
Fasting Glucose 3.9–5.5 mmol/L 4.5–5.2 mmol/L Stable energy availability
HbA1c <6.0% 5.0–5.4% Long‑term glucose control
Triglycerides <1.7 mmol/L <1.2 mmol/L Metabolic efficiency
HDL Cholesterol >1.0 mmol/L >1.3 mmol/L Protective lipid profile
LDL Cholesterol <3.0 mmol/L <2.5 mmol/L Lower cardiovascular risk
ALT / AST <40 U/L <30 U/L Liver stress marker

🧭 Decision Protocol

  1. Check fasting glucose: >6.1 mmol/L → escalate to doctor.
  2. Review HbA1c: >6.5% → diabetes threshold; 5.5–6.4% = pre‑diabetes risk.
  3. Assess lipids: High triglycerides or low HDL → metabolic stress.
  4. Check liver enzymes: ALT/AST >2× upper limit → escalate.
  5. Integrate with symptoms: fatigue, weight change, poor recovery → flag earlier.

🧍 Athlete Self‑Check

  • Unexplained weight gain or loss
  • Persistent fatigue despite adequate sleep
  • Cravings or energy crashes between meals
  • Slow recovery from normal training

If these symptoms persist alongside abnormal labs → escalate to medical review.

🗒 Coach Notes

  • Always interpret glucose and lipid results in the context of nutrition logs and training load.
  • Flag fasting glucose >5.5 mmol/L or HbA1c trending upward for medical review.
  • Look for patterns: repeated high triglycerides after camps may signal inadequate recovery or fueling.
  • Encourage athletes to track energy levels, mood, and sleep alongside labs.
  • Do not recommend supplements or medications — escalate to medical staff.

Reminder: Protect athlete health first; performance adjustments come only after medical clearance.

🛠 Role-Based Actions

Role Actions
🧑‍🎓 Rider • Maintain balanced meals with complex carbs, lean protein, healthy fats
• Avoid excessive processed sugar
• Track energy levels and recovery
• Report persistent fatigue or weight change
🧑‍🏫 Coach • Adjust training load if fatigue or poor recovery present
• Flag abnormal glucose or lipid results
• Encourage nutrition logging
• Coordinate re‑test in 8–12 weeks
🧑‍⚕️ Doctor / Nutritionist • Confirm diagnosis if abnormal
• Investigate insulin resistance or dyslipidemia
• Prescribe interventions if needed
• Monitor long‑term metabolic health

🔁 Feedback Loop

  • Re‑test 8–12 weeks after intervention or nutrition change
  • Escalate if:
    • Fasting glucose remains >5.5 mmol/L
    • HbA1c continues to rise
    • Triglycerides remain >1.7 mmol/L
    • ALT/AST remain elevated
    • Symptoms persist despite lifestyle adjustments

Tip: Record test date and planned re‑test date for accountability.

📚 Source Note

Ranges and decision logic adapted from WHO, ADA (American Diabetes Association), ESC/EAS lipid guidelines, and peer‑reviewed sports medicine literature. This panel is designed for transparency and athlete safety — always escalate red‑flag results to a qualified medical professional.

Biomarker Testing – Iron & Oxygen Transport Panel

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Iron & Oxygen Transport Panel

Version 1.0 | As at: 25 Sep 2025

Biomarkers

Panels

This protocol assesses iron status, oxygen transport capacity, and readiness for endurance load, heat, or altitude exposure. It supports safe training progression and helps identify deficiencies before they impact performance.

  • Supports endurance, heat, and altitude readiness
  • Flags iron deficiency, anaemia risk, or inflammation masking
  • Guides nutrition, training load, and supplementation timing
  • Provides context for fatigue, recovery, and adaptation

🚨 Red‑Flag Results — Seek Medical Review: Ferritin <30 µg/L • Hb below athlete range • Transferrin Saturation <15% • Persistent high CRP • Unexplained high ferritin

⏱ When to Test

  • Morning draw (before 10 AM) — aligns with low hepcidin
  • Rested 24–48 h post-hard training or racing
  • Well hydrated, no acute illness
  • Include CRP to interpret ferritin accurately
  • Recommended scenarios: start-of-base, pre/post altitude, pre/post heat, quarterly check, post-sickness

🧬 Athlete Targets

Marker Standard Range Athlete Target Notes
Ferritin 30–300 µg/L >50 µg/L (endurance); 70–100 µg/L (heat/altitude) Low ferritin = reduced iron stores
Haemoglobin M: 130–180 g/L; F: 120–160 g/L M: 145–165 g/L; F: 130–150 g/L O₂ carrying capacity
Haematocrit M: 0.40–0.52; F: 0.36–0.46 M: 0.44–0.48; F: 0.38–0.45 Supports Hb interpretation
Transferrin Saturation 15–45% >20%; avoid <15% Iron availability
sTfR 0.8–2.0 mg/L Lower half of range Iron demand marker
Hepcidin Varies Low in AM Iron absorption regulator
CRP <5.0 mg/L <1.0 mg/L Inflammation context

🧭 Decision Protocol

  1. Check CRP: If >3.0 mg/L → defer ferritin interpretation unless urgent.
  2. Storage & Demand: Low ferritin = low stores; High sTfR = increased demand.
  3. Transport Pattern: Transferrin ↑ + TIBC ↑ + Sat <20% → likely deficiency.
  4. Classify:
    • Absolute deficiency: Low ferritin, low Sat, high sTfR
    • Functional deficiency: Normal ferritin, high sTfR, low Sat
    • Inflammation-masked: Normal/high ferritin, high CRP, low Sat

🧍 Athlete Self‑Check

  • Persistent fatigue not explained by training load
  • Shortness of breath or dizziness
  • Unusual mood changes or irritability
  • Slow recovery after normal sessions

If these symptoms persist alongside abnormal labs → escalate to medical review.

🗒 Coach Notes

  • Always interpret iron results in the context of training load, recovery, and recent illness — don’t isolate the numbers.
  • Flag any athlete with ferritin <50 µg/L or Hb trending downwards for medical review, even if performance hasn’t dropped yet.
  • Look for patterns: repeated low iron after altitude or heat blocks may signal inadequate recovery or nutrition support.
  • Encourage athletes to log subjective fatigue, mood, and sleep alongside lab results — this builds a transparent picture of health.
  • Never prescribe supplements yourself; your role is to highlight concerns and coordinate with medical staff.

Reminder: Your role is to protect athlete health first. Performance adjustments come only after medical clearance.

🛠 Role-Based Actions

Role Actions
🧑‍🎓 Rider • Increase dietary iron (heme + non-heme + vitamin C)
• Time iron intake when hepcidin is low (AM, away from training)
• Monitor fatigue, mood, recovery
• Avoid iron supplements unless advised
🧑‍🏫 Coach • Adjust training load if symptoms present
• Flag low ferritin or Hb for follow-up
• Monitor performance drop, recovery lag, mood changes
• Coordinate re-test in 6–8 weeks
🧑‍⚕️ Doctor / Nutritionist • Confirm deficiency type (absolute, functional, masked)
• Prescribe iron supplements if needed
• Investigate persistent high ferritin or low Hb
• Address inflammation or absorption blockers

🔁 Feedback Loop

  • Re-test 6–8 weeks after intervention
  • Escalate if:
    • No improvement
    • Hb drops
    • Unexplained high ferritin
    • Persistent low Sat or high sTfR
    • Symptoms persist despite dietary changes

Tip: Record test date and planned re-test date here for accountability.

📚 Source Note

Ranges and decision logic adapted from WHO guidelines, IOC consensus statements, and peer‑reviewed sports medicine literature. This protocol is designed for transparency and athlete safety — always escalate red‑flag results to a qualified medical professional.